Combiflam Tablet Uses, Benefits, Combinations, Side-Effects and FAQ

Combiflam Tablet Uses, Benefits, Combinations, Side-Effects and FAQ

Combiflam tablet is a combination medicine used as  anti-inflammatory pain killers. It is used to relieve mild to moderate pain that is temporary. This medicine should be used with caution due to the increased risk of liver damage and bleeding complications.

Uses of Combiflam Tablet

Main uses are to relieve pain like



Muscle pain

Joint pain

Back pain

Post-operative pain

Pain during menstruation

Pain due to osteoarthritis and rheumatoid arthritis

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Combiflam Tablet composition, active content composition and active ingredients

It contains Ibuprofen and Paracetamol as active ingredients

Paracetamol is an analgesic (pain reliever) and antipyretic (fever reducer)

Ibuprofen is a non-steroidal anti-inflammatory drug

How Combiflam Works in the body?

During pain our body releases some chemicals like prostaglandin. If we stop these chemical then can get relieve in pain.

So, paracetamol and ibuprofen components of combiflam works by blocking the production of chemicals. Because these chemicals cause pain, fever and inflammation.

Packages and capabilities

Combiflam Strength:  400mg/325mg

Packing: 1×20

Type: Tablet

Combiflam Tablet Side Effects

Allergic reaction

Abdominal pain


Decreased urine output in severe case





Heartburn in severe case

Nausea or Vomiting


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How to Use/take Combiflam Tablet

Swallow it as a whole. Do not chew, crush or break it. It is better to take Combiflam Tablet with food.

Inform your doctor before taking this tablet about your current list of medications, over the counter products (e.g. vitamins, herbal supplements). Allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery). Some time it causes side-effects. Take medicine as directed by your doctor Dosage is based on your condition.

Drug Interaction of Combiflam Tablet

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, rashes, nausea, joint pain, fever.

It can interact severely with these drugs like:


Sodium Nitrite



Drug interact moderately with these drugs like:







Avoid taking alcohol

Avoid using it if allergic to paracetamol

Consult with your doctor if you develop blurred vision, ringing or roaring in ears

Inform your doctor if you have bruising or bleeding

Take the drug with a meal or snack to prevent upset stomach

This medicine should be used with caution in patients with anaemia due to the increased risk of worsening of the patient’s condition

Combiflam Tablet should be used with caution in patients with liver disease

Use of Combiflam Tablet is not recommended in patients with severe kidney disease. Long term use of this medicine can affect the kidney function

Prohibition / Contraindications

Hypersensitivity to combiflam tablet is a contraindication. In addition, combiflam tablet should not be used if you have the following conditions:

Active peptic ulcer


Gastrointestinal bleeding

Hepatic impairment



Not recommended in patients with known conditions like asthma, rhinitis, and urticarial

Not recommended in patients with recent heart surgery

Frequently Asked Questions

Is Combiflam tablet safe?

Yes, this tablet is safe if it is taken by prescription of the doctor.

Can combiflam tablet take along with methotrexate?

Tablet may increase the blood levels of methotrexate and can cause liver injury, breathing problem, and bleeding.

Can you take aspirin and combiflam together?

Combiflam Tablet may reduce the effect of aspirin and increases the risk of bleeding.

What happens if you take an overdose of combiflam tablet?

Overdose of this medicine can cause life-threatening condition like liver damage, which is the most serious side effect. Early symptoms may include nausea, vomiting, profuse sweating, and general tiredness.

Can we take this medicine during pregnancy?

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Can we take this medicine during breastfeeding?

This medicine is not recommended for use in breastfeeding women unless absolutely necessary.

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